Макарова М.Н.

Rabbits in preclinical research

Risk-based approach to the health monitoring of rabbits

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 8: syrian hamsters

Non-human primates in preclinical development of monoclonal antibodies

Recommended and maximum allowable volumes for rectal and intravaginal administration of drugs of different animal species

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies Part 9: cats

Determination of reference intervals of creatinine clearance in laboratory animals

Pharmacokinetics of new analgesic tridecapeptide with an octaarginine vector investigated after original analytical approach

Альтернативные методы по оценке токсичности в рамках этической экспертизы. Обзор

THE EFFECT OF FIXING SOLUTIONS ON THE SEVERITY OF ARTIFACTS IN THE RETINA AND CHOROID IN HISTOLOGICAL SECTIONS OF THE RABBIT EYE

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 5: ferrets

Risk-based approach to the health monitoring of primates

Evaluation of nesting behavior as an indicator of the level of distress in laboratory mice

The use of vitals as intermediate points in preclinical trials of pharmaceuticals in dwarf pig models

Toxicological studies. Reference intervals of mass coefficients of internal organs in a sample of 1000 rats

The use of inhalantational anaesthesia in preclinical studies

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 3: mini pigs

Dynamics of age changes of somatotropin concentration in blood plasma and morphometric parameters of laboratory female mice ovaries

New in the science and practice of preclinical research. Report 2

Endotracheal administration to laboratory animals

New in the science and practice of preclinical research

Circadian fluctuation in plasma testosterone levels in adult male rats

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 2: rabbit

Variability of blood biochemical parameters and establishing of reference ranges in nonclinical studies. Part 1: rats

Facilities of the Breeding Performance of BALB/с mice

Preclinical study of monoclonal antibodies (MAT). Report 1: experimental models for the assessment of MAT in respiratory diseases

Impact Assessment оf Potential Risks From Enviromental Temperature Decrising оf Laboratory Animals (Mice, Rats, Guinea Pigs) Outside the Recommended Range for Main Biological Parameters

Duration of bactericidal effect of UV lamps in vivarium. Sources of air contamination in vivarium

The respiratory rate in preclinical studies

Impact assessment of potential risks from warmer enviromental temperature of laboratory animals (mice, rats, guinea pigs) outside the recommendated range for main biological parameters

Technique of dissection and extracting organs of laboratory animals. Message 5 – rabbit, ferret

Diet-induced models of metabolic disorders. Report 7: Experimental osteoporosis

Intranasal Introduction to Laboratory Animals

Technique of Dissection and Extracting Organs of Laboratory Animals. Message 4: Guinea Pig, Gerbil, Degu

Diet-induced Models of Metabolic Disorders. Report 6: Experimental Anemia

Development of a Model of Immunosuppression in Rabbits Caused by Intravenous Administration of Cyclophosphamide

Experimental Animal Models Of Acute Bronchitis

Features Of Working With Laboratory Animals In Microbiological Laboratory

Diet-Induced Models Of Metabolic Disorders. Report 5: Experimental Hypertension

Audit Of Preclinical Research Center. Main Directions

A Comparative Study Of The Use Of High-Calorie Diets Enriched By Different Number Of Lipids For Modeling Metabolic Syndrome

Technique Of Dissection And Extracting Organs Of Laboratory Animals. Message 3 − Hamster

Regulatory Framework Experimental Biological Clinics (Vivaries) And Nursery For Laboratory Animals

Assessment Criteria Of Experimental Endometrios In Rats

Experience Of Magnusson And Kligman Guinea Pigs Maximization Test In Studies Of The Sensitizing Potential Of Chemical Substances

Technique Of Dissection And Extracting Organs Of Laboratory Animals. Message 2: Mouse

Diet-Induced Models Of Metabolic Disorders. Report 4: Experimental Nonalcoholic Fatty Liver Disease

Spontaneous Age-Related Pathology Of The Urinary System In Rats

Caenorhabditis Elegans As A Model Object For Biomedical Studies

Regulatory And Methodical Aspects Of Pre-Clinical And Clinical Studies Of Feed Additives For Animals

Recommendations For Testing The Diabetogenic Activity Of Streptozotocin

Diet-Induced Models Of Metabolic Disorders. Report 3: Experimental Diabetes

Basic Requirements And Features Of Methodology Of The Vascular Permeability Model

Pathomorphological Diagnostics Of Lungs At Various Methods Of Euthanasia Of Laboratory Animals

Comparative Morphology Of The Pancreas Of Experimental Animals And Humans

Technique Of Dissection And Extracting Organs Of Laboratory Animals. Message 1 (Rats)

Some Features Of Fixation Of Organs And Tissues Of Laboratory Animals For Quality Of Gistological Analysis

Experience Of Modeling Of Non-Alcohol Stemathegatitis With Use Of Methyonin-Holin Deficient Diet On The Mouse Of The C57BL/6 Line

Diet-Induced Models Of Metabolic Disturbances. Report 2: Experimental Obesity

Zootechnical Characteristics Of Gerbils Keeping In Experimental Vivarium

Effect Of Different Species Of Anesthesia On Electrocardiogram Parameters In Rats

Diet-Induced Models Of Metabolic Disorders. Experimental Metabolic Syndrome

Histological Evaluation Of Joint Pathology In Various Models Of Chronic Arthritis In Rats

Review Of Genetically Modified Lines Of The Laboratory Animals Used As Model Metabolic Syndrome And Diabetes Mellitus Models

Bioethical And Economic Aspects In The Basis Of A Choice Of A Method Of Studying Of Toxicity Of Medical Products At Single Introduction

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Zootechnical Characteristics Of Gerbils Keeping In Experimental Vivarium
The article presents a literature review of biological features, zootechnical characteristics of content and breeding, as well as models of pathologies most frequently reproduced in the Mongolian gerbils.
Research of the biocompatibility of composite materials based on hydroxyapatitis and copolymer lactide-glycolide on laboratory mice
. In this study, the biocompatibility of composite materials based on hydroxyapatite and the copolymer lactide and glycolide with different ratios of components was studied on mice: composite material No. 1 – 95: 5 wt%, composite material No. 2 – 93: 7 wt%.
Technique Of Dissection And Extracting Organs Of Laboratory Animals. Message 3 − Hamster
The third message from the series of articles on the methodology of necropsy and extraction organs of laboratory animals, describing in detail and illustrating the technique of sequential and complete autopsy and extraction of organs of laboratory hamsters.
Recurrent Hypoglicemia Affects S100B Plasma Concentration And S100b Hippocampal Expression In Rats
A significant decrease in blood glucose levels leads to the development of delayed cognitive impairment, caused by hypoglycemia damage of brain neurons.
Effect Of Different Species Of Anesthesia On Electrocardiogram Parameters In Rats
The electrocardiogram (ECG) is one of the most common diagnostic tools in medicine. The ECG record reflects the electrical activity of the heart and can provide information about the functional and structural characteristics of the myocardium.
Evaluation of the use of various formula for correction of the QT interval (QTC) and ECG reference intervals in anesthetized beagle dogs
Safety pharmacology is an essential stage of preclinical testing strategy and includes studies evaluating the potential effects of a test substance on vital systems: the cardiovascular, respiratory and central nervous systems.

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