The article summarizes information on the basic characteristics associated with the genetically determined level of excitability of the nervous system, as well as long-term stable changes in behavior, morphological, genetic and epigenetic modifications caused by long-term emotional and painful st

Today, one of the main reasons for the spread of insulin resistance, which subsequently leads to the development of obesity, type 2 diabetes and metabolic syndrome (MS), is the peculiarity of modern human eating behavior, its propensity to unlimited intake of high-calorie food.

On the center of experimental pharmacology Saint-Petersburg Chemical-Pharmaceutical University on rabbits male breed of Soviet chinchilla, as the most accessible and relevant test system, was conducted modeling of traumatic erosion by the method of S. Hanna, J.E.

The results of a comparative study of the intravital cytological material of the columnar ciliated epithelium of the nasal cavity from intact adult rats of the Wistar (220-250 g) contained in the conventional type vivarium (n = 2) and SPF category (n = 2) are presented.

The welfare of laboratory animals is essential to ensure quality of the experiments. Unfortunately, the few Quality Assurance Specialist of pharmaceutical companies are veterinarians, therefore could hardly fully evaluate these issues.

mployees of RIHOPHE carried out the development and assembly of a modified shuttle box device, intended for the implementation of the URAI test (conditioned reflex of active avoidance). This method allows to study the dynamics of training of rodents in conditions of electrobolic stress.