Makarova M.

The welfare of laboratory animals is essential to ensure quality of the experiments. Unfortunately, the few Quality Assurance Specialist of pharmaceutical companies are veterinarians, therefore could hardly fully evaluate these issues.

The aim of this study was to develop a model for the development of hyperalgesic priming using loperamide in rats.

The electrocardiogram (ECG) is one of the most common diagnostic tools in medicine. The ECG record reflects the electrical activity of the heart and can provide information about the functional and structural characteristics of the myocardium.

Summary. Assessment of mutagenic properties of a new drug is an important part of its preclinical trials, because allows to study the drug’s ability to induce different mutations in fetal and somatic cells.

Summary. Nonalcoholic fatty liver disease (NAFLD) is one of the most frequently diagnosed chronic liver diseases, in the etiology of which a special role is played by increasing the proportion of sucrose, fructose and fat in the structure of the diet of the population.