Sakovich P.V.

The fourth message from the series of articles on the methodology of necropsy and extraction organs of laboratory animals, describing in detail and illustrating the technique of sequential and complete autopsy and extraction of organs of laboratory guinea pigs, gerbils and degu.

When an influence of various toxic substances or prospective medicines on an organism is estimated, the concentration of the substance in question in tissues must be evaluated.

Recently, in studies on the mechanisms of lifespan in animal models, the attention of scientists around the world has attracted Heterocephalus glaber, a unique rodent species originating from the Horn of Africa.

Urinalysis is an essential part of preclinical researches of drugs. It is carried out to determine the clinical state of animals’ health, assess the results of experimental manipulations, as well as the effect of drugs on the urinary system.