Viability studies are carried out to measure the proportion of viable cells after exposure to a substance, drug or manipulation, for example, in studies of cytotoxicity or proliferative activity, after cryostorage or cell division, and etc.
The pancreas is an unpaired parenchymal organ that belongs to the glands of mixed secretion. It includes the exocrine and endocrine parts, while participating in digestion, and in the regulation of carbohydrate, protein and fat metabolism in tissues.
The article discusses the importance of integration of pharmacokinetics in toxicity testing. This will be helpful in interpretation of the results of toxicological studies and ensure the development of a rational study design.