The welfare of laboratory animals is essential to ensure quality of the experiments. Unfortunately, the few Quality Assurance Specialist of pharmaceutical companies are veterinarians, therefore could hardly fully evaluate these issues.
Summary. An instrumental method/device for detecting of estrous stages in small rodents was tested in mice and rats. Cyclic changes in active resistance (RS) of the epithelial cell layer of vaginal mucosa were studied with a new mouse estrous detector device - MED-PRO 100 (Elmi Ltd., Latvia).
Today, one of the main reasons for the spread of insulin resistance, which subsequently leads to the development of obesity, type 2 diabetes and metabolic syndrome (MS), is the peculiarity of modern human eating behavior, its propensity to unlimited intake of high-calorie food.
Summary. Nonalcoholic fatty liver disease (NAFLD) is one of the most frequently diagnosed chronic liver diseases, in the etiology of which a special role is played by increasing the proportion of sucrose, fructose and fat in the structure of the diet of the population.
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