The Impact Of Shiitake Mushroom (Higher Basidiomycetes) On Сopulatory Behaviour Of Mammals: Social Vole Microtus Socialis

DOI: 10.29296/2618723X-2018-03-03

T. Zorenko, PhD, Associative Professor, I. Motmillere, Master of Science, N. Matjushkova, Doctor of Science, Associative Professor Faculty of Biology University of Latvia University of Latvia, Jelgava’s str. 1, Riga, LV-1586 Е-mail: [email protected]

Keywords: shiitake mushroom oyster mushroom copulatory behaviour libido mammal social vole Microtus socialis
For citation:

Zorenko T., Motmillere I., Matjushkova N. The Impact Of Shiitake Mushroom (Higher Basidiomycetes) On Сopulatory Behaviour Of Mammals: Social Vole Microtus Socialis. Laboratory Animals for Science. 2018; 3. https://doi.org/10.29296/2618723X-2018-03-03

Abstract

In recent years, voles (Rodentia, Cricetidae) are often used in various biological studies, which because of their behavioural and physiological characteristics represent a convenient laboratory object. The results of the experiments indicate a high aphrodisiac activity of shiitake mushrooms. A three-week diet supplemented with an aqueous extract of shiitake led not only to the restoration of sexual motivation in males with initially decreased libido, but also to an increase in the number of ejaculations 1.5 times, and the total duration of mating 1.8 times (19.4 min). A control diet was supplemented with wheat bran (Control-1) or an extract of oyster mushroom (Control-2). It restored the attraction to the female and mating, but did not change the mating parameters; moreover, in Control-2 (oyster mushroom), the parameters were lower than in the average species norm. In males with a initially normal sexual motivation, the aphrodisiac effect of the aqueous extract of shiitake was even more significant. Not only statistically significantly increased mating parameters, such as the number of ejaculations and the total duration of mating, but also the number of thrusts that determine increased genital stimulation, which is important for more successful fertilization of the female and obtaining a greater number of offspring. Oyster extract also caused an increase in the number of ejaculations, although significantly less than in males that received shiitake extract. In addition, it did not affect other parameters of mating. The mechanism of action of mushrooms on the sexual activity of animals has not yet been established. Various hypotheses of this influence are discussed. We assume that many of the components of fungi such as lentinan, Zn, carnitine and etc. have an cumulative effect, causing an improvement in the activity of the males, as well as the quality their sperms (density and motility of the spermatozoa). As a result, increase the vitality and energy of the organism i.e. libido.

References

  1. Chang S.-T., Buswell J.A., Miles P.G. Genetics and Breeding of Edible Mushrooms. Netherlands: Gordon and Breach Science Publishers. 1999; 1–324.
  2. Hobbs C.R. Medicinal value of Lentinus edodes (Berk.) Sing. (Agaricomycetideae). A literature review. Int. J. Med. Mushrooms. 2000; 2: 287–302.
  3. Wasser S.P. Shiitake (Lentinus edodes). Encyclopedia of dietary supplements. Coates P.M, Blackman M.R., Cragg G.M., Levine M., Moss J., White J.D. (editors). New York, Marcel Dekker. 2005; 653–64. DOI: 10.1081/E-EDS-120024880.
  4. Powell M. Medicinal mushrooms: A clinical guide. East Sussex, Mycology Press. 2010.
  5. Sozens D.D., Masters R.E., Clark R., Offer J.M. The effect of lentinan on fertility and general reproductive performance of the rat // Tox. Letters. 1981; 9: 55–64.
  6. Sozens D.D., Hughes E.W., Clark R., Offer J.M. The effect of lentinan on the in uterus embryonic and foetal development of rat and on postnatal development of the F1 offspring. Tox. Letters. 1981; 9: 71–6.
  7. Sozens D.D., Masters R.E., Clark R. The effect of lentinan on pregnancy of the New Zealand white rabbit. Toxicology Letters. 1981; 9: 65–9.
  8. Zorenko T., Matjushkova N., Muiznieks I. The effect of mushroom shiitake on ontogenesis and reproduction of the social vole Microtus socialis (Rodentia, Cricetidae). Baltic Journal of Laboratory Animals Science. 2003; 13: 69–77.
  9. Zorenko T., Motmillere I., Matjuskova N. Does the feeding with shiitake mushrooms increase reproductive capacity of mammals? The 3d International Symposium “Physiological bases for increasing the productivity of mammals introduced in zooculture”. 2005. Petrozavodsk on 27–29 Sept. 2005; 72–4.
  10. Hwang J.A., Hossain M.E., Yun D.H., Moon S.T., Kim G.M., Yang C.J. 2012. Effect of shiitake [Lentinula edodes (Berk.) Peglerh mushroom on laying performance, egg quality, fatty acid composition and cholesterol concentration of eggs in layer chickens. J. Med. Plants Res. 2012; 1: 146–53.
  11. Djordjevic B., Škugor S., Jųrgensen S.M., Ųverland M., Mydland L.T., Krasnov A. Modulation of splenic immune responses to bacterial lipopolysaccharide in rainbow trout (Oncorhynchusmykiss) fed lentinan, a beta-glucan from mushroom Lentinula edodes. Fish&Shell fish Immuno. 2009; 26 (2): 201–9.
  12. Motmillere I., Zorenko T., Matyushkova N. Uluchshenie reproduktivnyh pokazateley, razvodimyh v nevole mlekopitayushhih s pomoshh`yu podkormki ih e`kstraktom griba shiitake. Sovremennye problemy prirodopol`zovaniya, ohotovedeniya i zverovodstva. Mezhdunarodnaya nauchno-prakticheskaya konferenciya. Kirov. 2007; 303–4.
  13. Svilpe E., Matjushkova N. Influence of shiitake muschroom Lentinula edodes on reproduction of Drosophila melanogaster. Proceeding of the Latvian Academy of Science. Section B. 2010; 64 (5/6): 223–8. DOI: 10.2478/v10046-010-0008-2.
  14. Zorenko T.A. Obshhestvennye polevki podroda Sumeriomys (sistematika, biologiya i povedenie). 2013; LAP Lambert Academic Publishing: 1–541.
  15. Dewsbury D.A. Patterns of copulatory behaviour in male mammals. Quarterly Review of Biology. 1972; 47 (1): 1–33.
  16. Chihara G., Hamuro J., Maeda Y., Arai Y., Fukuoka F. Fractionation and purification of the polysaccharides with marked antitumor activity especially lentinan, from Lentinus edodes (Berk). Cancer Res. 1970; 30: 2776–81.
  17. Zorenko T.A., Skinderskaya I.A. Polovye cikly i povedencheskaya receptivnost` u samok obshhestvennyh polevok podroda Sumeriomys (Rodentia, Arvicolinae). Zool. zhurn. 1996; 75 (10): 1735–47.
  18. Zorenko T.A. Morfologiya genitaliy i polovoe povedenie obshhestvennyh polevok podroda Sumeriomys (Arvicolinae, Microtus). Zoologicheskiy zhurnal. 2000; 79 (8): 990–9.
  19. Zorenko T., Motmillere I. Ot chego zavisit reproduktivnyy uspeh samcov obshhestvennoy polevki? Povedenie i povedencheskaya e`kologiya mlekopitayushhih. Materialy mezhdunarodnogo soveshhaniya, Chernogolovka. 2007; 245–8.
  20. Hotimchenko Yu.S., Kropotov A.V., Lisakovskaya O.V. Prirodnye adaptogeny v regulyacii polovyh funkciy cheloveka i zhivotnyh. Vestnik DVO RAN. 1996; 5: 15–24.
  21. Kropotov A.V., Lisakovskaya O.V., Hotimchenko Yu.S. Sezonnye osobennosti vliyaniya adaptogenov na polovoe povedenie e`ksperimental`nyh zhivotnyh. E`ksperimental`naya i klinicheskaya farmakologiya. 2001; 64 (6): 60–2.
  22. Kropotov A.V., Lisakovskaya O.V., Yur`eva M.I., Plaksen N.V., Hil`chenko N.S., Goncharova R.K. Vliyanie adaptogenov ili racionov, soderzhashhih ikru morskih ezhey, na polovoe povedenie samcov krys. Tihookeansk. med. zhurn. 2009; 1: 32–5.
  23. Gunde-Cimerman N. Medicinal value of the genus Pleurotus (Fr.) P.Karst. (Agaricaless l, Basidiomycetes). International Journal of Medicinal Mushrooms, 1999; 1 (1): 69–80.
  24. Gunde-Cimerman N., Plemenitaš A. Hypocholesterolemic activity of the genus Pleurotus (Jacq. Fr.) P. Kumm. (Agaricales s. I., Basidiomycetes). International Journal of Medicinal Mushrooms. 2001; 3 (4): 395–7.
  25. Patel Y., Naraian R., Singh V.K. Medicinal properties of Pleurotus species (oyster mushroom): A review. World Journal of Fungal and Plant Biology. 2012; 3 (1): 1–12.
  26. Khatun K., Mahtab H., Khanam P.A., Sayeed M.A., Khan K.A. Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Mymensingh Medical Journal. 2007; 16 (1): 94–9.
  27. Flynn V.T., 1991. Is the shiitake mushroom an aphrodisiac and a cause of longevity? In: Maker, M.J. (Ed.), Science and Cultivation of Edible Fungi. Balkema, Rotterdam, pp. 345–61.
  28. Miles P.G., Chang S-T. Mushroom Biology. Concise Basics and Current Developments. World Scientific, Singapore. 1997: 1–194.
  29. Zhang M., Cui S. W., Cheung P. C. K., Wang, Q. Antitumor polysaccharides from mushrooms: A review on their isolation process, structural characteristics and antitumor activity. Review. Trends in Food Science & Technology. 2007; 18: 4–19.
  30. Lee H.H., Lee J.S., Cho J.Y., Kim Y.E., Hong E.K. Structural characteristics of immunostimulating polysaccharides from Lentinus edodes. J. Journal of Microbiology and Biotechnology 2009; 19 (5): 455–61.
  31. Kabir Y., Yamaguchi M., Kimura S. Effect of shiitake (Lentinula edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. Journal of Nutritional Science and Vitaminology. 1987; 33: 341–6.
  32. Virag R. Is impotence an Arterial Disorder? The Lancet. 1985; 26: 181–4.
  33. Antoniou L.D., Shalhoub R.J., Sudhavar T. and Smith J.C., Reversal of uremic impotence by zinc. The Lancet. 1977; 2: 895–8.
  34. Reguła J., Gramza-Michałowska A. Effect of the addition of dried shiitake (Lentinula edodes) to corn crackers on their chemical composition and ability to bind Fe(III) and Zn(II) – a short report. Polish journal of food and nutrition sciences. 2009; 59 (3): 275–8.
  35. Zorenko T.A., Motmillere I., Dambrova M.U., Matyushkova N.A. Veroyatnaya rol` karnitina v polovom povedenii samcov obshhestvennoy polevki. 4-ya Vseross. konf. po povedeniyu zhivotnyh. M., 2007: 598–9.
  36. Cavallini G., Cracciolo S., Vitali G., Modenini F., Biagiotti G. Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging. Adult Urology. 2004; 63: 641–6.
  37. Coates P.M, Blackman M.R., Cragg G.M., Agarwal A, Said TM. Carnitines and male infertility. Reproductive BioMedicine Online. 2004; 8: 376–84.
  38. Sinclair S. Male infertility: nutritional and environmental considerations. Alternative Medicine Review. 2000; 5: 28–38.
  39. Ahmed S.D., Karira K.A, Jagdesh, Ahsan S. Role of L-carnitine in male infertility. Journal of Pakistan Medical Association. 2011; 61 (8):732–6.

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