Beltyukov P.P.

In recent years,_ Galleria mellonella_, the larvae of a large wax moth, has been widely used as an alternative model for studying bacterial infections, as well as for evaluating the effectiveness of antibacterial drugs.

The Mongolian gerbil — Meriones unguiculatus — has been used in biomedical research recently compared to other rodents (mice, rats, guinea pigs). The gerbil is generally non-aggressive and is one of the easiest rodents to keep and handle.

The article discusses the importance of integration of pharmacokinetics in toxicity testing. This will be helpful in interpretation of the results of toxicological studies and ensure the development of a rational study design.