Standards for the maintenance of laboratory animals in nurseries by zoolaborants

Original article

УДК 636.028; 331.108

DOI: 10.57034/2618723X-2024-01-05

M.A. Akimova*,
chief livestock specialist,
https://orcid.org/0000-0001-8643-3613
M.N. Makarova,
MD, Director,
https://orcid.org/0000-0003-3176-6386
S.V. Gushchina,
Validator and Statistician,
https://orcid.org/0000-0002-0247-0378
T.G. Barmina,
livestock specialist,
https://orcid.org/0000-0002-7807-0768
E.V. Vesnina,
livestock specialist,
https://orcid.org/0000-0003-4876-1397
D.Yu. Akimov,
chief veterinarian,
https://orcid.org/0000-0003-3141-492X

Research and manufacturing company “Home оf Pharmacy”,
188663, Russia, Leningrad oblast, Vsevolozhskiy district, Kuzmolovskiy t.s., Zavodskaya st. 3–245.

*E-mail: [email protected]

Keywords: labour zoolaborant life support of laboratory animals

Acknowledgements

The study was performed without external funding.

For citation:

Akimova M.A., Makarova M.N., Gushchina S.V., Barmina T.G., Vesnina E.V., Akimov D.Yu. Standards for the maintenance of laboratory animals in nurseries by zoolaborants. Laboratory Animals for Science. 2024; 1. https://doi.org/10.57034/2618723X-2024-01-05

Abstract

The foundation of all research using laboratory animals is to meet the basic needs of any living organism. The personnel responsible for the life support of laboratory animals belongs to category “A”. The purpose of our research was to create an approach for rationing the working day of zoo laboratory laboratory animals. Based on the goal, the following tasks were set: To characterize the work tasks of zoolaborants depending on the type of laboratory animals being serviced. Determine the time of manipulations performed by zoolaborants. Establish standards for the maintenance of laboratory animals for 1 employee for 1 work shift. As a result of the study, the main work tasks of zoo assistants serving mice, rats, gerbils, hamsters, guinea pigs, rabbits, dwarf pigs, ferrets, cats, dogs, Javanese macaques and common igrunks were characterized. Differences in labor tasks have been established depending on the type of maintenance of laboratory animals (cages or boxes). When servicing rodents, rabbits and ferrets contained in cages that require replacement, the work tasks of zoolaborants are divided into: preparation of clean cells for replacement, cell replacement, feeding, watering, cleaning/general cleaning and disinfection. When servicing cats, dogs, dwarf pigs that are kept in boxes, labor tasks are cleaning the box, feeding and watering. For primates (Javanese macaques and common monkeys) kept in stationary cages that do not require cell replacement, the work tasks of zoo laboratory assistants are cleaning the cage, feeding and watering. The average execution time of each labor task by a zoolaborant has been established, depending on the type of laboratory animals served. The standards of service of animals for 1 employee for 1 work shift are calculated. The data obtained make it possible to plan the number of zoolaborants and the production rate depending on the type and number of animals served. Together, the above factors can influence the formation of calculations of the full-time (normative) number of employees involved in the maintenance of laboratory animals when creating a nursery or when introducing a new type of test systems.

Conflict of interest

M.N. Makarova is a member of the editorial board of Laboratory animals for science.

Authors contribution

M.A. Akimova — implementation of the experimental part, collection and systematization of material, writing the text of the article.
M.N. Makarova — editing and approval of the final version of the article for publication.
S.V. Gushchina — analysis and statistical processing of data.
T.G. Barmina — performing the experimental part.
E.V. Vesnina — execution of the experimental part.
D.Yu. Akimov — working with tabular data and drawings.

Приказ Минздравсоцразвития РФ от 15.02.12 № 126н «Об утверждении Единого квалификационного справочника должностей руководителей, специалистов и служащих, раздел «Квалификационные характеристики должностей работников сельского хозяйства» // СПС: КонсультантПлюс. [Prikaz Minzdravsoczrazvitiya RF ot 15.02.12 N. 126n “Ob utverzhdenii Edinogo kvalifikacionnogo spravochnika dolzhnostej rukovoditelej, specialistov i sluzhashhix, razdel “Kvalifikacionny’e xarakteristiki dolzhnostej rabotnikov sel’skogo xozyajstva”, SPS: Konsul’tantPlyus. (In Russ.)].
Постановление Минтруда РФ от 10.11.1992 № 31 (ред. от 24.11.2008 № 665) [утв. Министерством труда Российской Федерации 10 ноября 1992 г.] «Об утверждении тарифно-квалификационных характеристик по общеотраслевым профессиям рабочих». [Postanovlenie Mintruda RF ot 10.11.1992 № 31 (red. ot 24.11.2008 N. 665) {utv. Ministerstvom truda Rossijskoj Federacii 10 noyabrya 1992 g.} “Ob utverzhdenii tarifno-kvalifikacionny'x xarakteristik po obshheotraslevy'm professiyam rabochix”. (In Russ.)].
Приказ Минздрава СССР от 31.12.1981 № 1358 «Об утверждении Отраслевых норм обслуживания лабораторных животных». [Prikaz Minzdrava SSSR ot 31.12.1981 N. 1358 “Ob utverzhdenii Otraslevy’x norm obsluzhivaniya laboratorny’x zhivotny’x”. (In Russ.)].
РД-АПК № 3.10.07.02–09 от 01 декабря 2009 г. «Методические рекомендации по содержанию лабораторных животных в вивариях научно-исследовательских институтов и учебных заведений». [RD-APK N. 3.10.07.02–09 ot 01 dekabrya 2009 g. “Metodicheskie rekomendacii po soderzhaniyu laboratorny’x zhivotny’x v vivariyax nauchno-issledovatel’skix institutov i uchebny’x zavedenij”. (In Russ.)].
Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes Text with EEA relevance.
«Трудовой кодекс Российской Федерации» от 30.12.01 № 197‑ФЗ (ред. От 19.12.22) (с изм. и доп., вступ. в силу с 01.03.23) ТК РФ Статья 108. Перерывы для отдыха и питания. [“Trudovoj kodeks Rossijskoj Federacii” ot 30.12.01 N. 197‑FZ (red. Ot 19.12.22) (s izm. i dop., vstup. v silu s 01.03.23) TK RF Stat’ya 108. Perery’vy’ dlya otdy’xa i pitaniya. (In Russ.)].

References

Консультант GLP-PLANET. Мнение фармацевтической отрасли: Монография / Под редакцией В.Г. Макарова, В.Н. Шестакова. Москва: Издательский дом «Русский врач», 2021. 168 с. [Konsul’tant GLP-PLANET. Mnenie farmatsevticheskoi otrasli: Monografiya / Pod redaktsiei V.G. Makarova, V.N. Shestakova. Moskva: Izdatel’skii dom “Russkii vrach”, 2021. 168 p. (In Russ.)]. DOI: 10.29296/978-5-7724-0177-4.
Консультант GLP-Planet 2022. Мнение фармацевтической отрасли. Санкт-Петербург: Акционерное общество «Научно-производственное объединение «ДОМ ФАРМАЦИИ», 2022. 248 с. [Konsul’tant GLP-Planet 2022. Mnenie farmatsevticheskoi otrasli. Sankt-Peterburg: Aktsionernoe obshchestvo “Nauchno-proizvodstvennoe ob’edinenie “DOM FARMATSII”, 2022. 248 p. (In Russ.)].DOI: 10.57034/978-5-6048955-0-4.
Каркищенко Н.Н. Альтернативы биомедицины / Н.Н. Каркищенко. Том 1. Москва: Межакадемическое издательство ВПК, 2007. 319 с. [Karkishchenko N.N. Al’ternativy biomeditsiny / N.N. Karkishchenko. Vol. 1. Moskva: Mezhakademicheskoe izdatel’stvo VPK, 2007. 319 p. (In Russ.)].
Свидетельство о государственной регистрации базы данных № 2015620023 Российская Федерация. Методическое пособие по нормированию труда и материальных ресурсов для планирования и прогнозирования отраслей животноводства Республики Саха (Якутия): № 2014620598: заявл. 05.05.2014: опубл. 12.01.2015 / Г.И. Даянова, Т.А. Никонова, Ф.Д. Халтанова, А.Т. Матвеев; заявитель Государственное научное учреждение Якутский научно-исследовательский институт сельского хозяйства Российской академии сельскохозяйственных наук. [Svidetel’stvo o gosudarstvennoi registratsii bazy dannykh № 2015620023 Rossiiskaya Federatsiya. Metodicheskoe posobie po normirovaniyu truda i material’nykh resursov dlya planirovaniya I prognozirovaniya otraslei zhivotnovodstva Respubliki Sakha (Yakutiya): № 2014620598: zayavl. 05.05.2014: opubl. 12.01.2015 / G.I. Dayanova, T.A. Nikonova, F.D. Khaltanova, A.T. Matveev; zayavitel’ Gosudarstvennoe nauchnoe uchrezhdenie Yakutskii nauchno-issledovatel’skii institut sel’skogo khozyaistva Rossiiskoi akademii sel’skokhozyaistvennykh nauk. (In Russ.)].

Received: 2023-11-21

Reviewed: 2023-12-07

Accepted for publication: 2024-02-05

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