Karal-оgly D.D.

Primates as a model for research

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Model of diet-induced experimental diabetes mellitus in laboratory gerbils and degus
According to the latest data from the International Diabetes Federation (IDF), the number of patients with diabetes has outpaced previously predicted growth rates and is expected to increase by 51% by 2045.
Experience with an optimized methodology of safety studies for pediatric medicines using the example of a drug containing cattle cerebral cortex polypeptides
This article presented the results of an experimental preclinical toxicological study of the drug containing cattle cerebral cortex polypeptides concerning the health indicators of immature animals.
Allergy to laboratory rodents: the underestimated problem
In the present review, we discuss the problem of hypersensitivity to laboratory animal allergens, which affects both animal caretakers and research personnel. Biological characteristics of the main allergens released by laboratory rodents are presented, as well a
Application of morphometry methods to assess histopathology in preclinical studies
Morphometry is one of the most important methods of preclinical studies. It is an integral part of microscopy analysis.
Zootechny of laboratory gerbils
For the maintenance of laboratory gerbils, which are a valuable test system in preclinical studies, it is necessary to pay attention to such zootechnical parameters as the conditions of their placement, taking into account the parameters of the microclimate, feeding rations appropriate to their n
The methods of visualization and research of the git-associated lymphoid tissue of laboratory animals
The immune system is an important part of the vital activity in the organism, because it prevents a penetration of foreign bodies and substances or it deletes them very quickly.

Karal-оgly D.D.

Primates as a model for research

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